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Efficacy Research

Diabetes
Obesity
Osteoporosis
Orthopedic
Ophthalmic
Nutrition
Transdermal Drug Delivery
Reproduction
Pediatrics
Transgenics
Transplantation

Pharmacology Research

Range of Species:
- Rodents
- Rabbits
- Large Canine Colony
- Miniature Swine
- Other Species: Cats, Sheep, Goats, Horses, Poultry
Pharmacokinetics/Bioavailability:
- Various delivery routes in all animal species including transdermal delivery in miniature swine
- Vascular Access Port (VAP) placement in miniature swine for pharmacokinetics
- Canine intestinal cannulation
Toxicokinetics
Pharmacodynamics
Metabolism, Tissue Disposition, Biodistribution
Experience with a variety of test articles, including small molecules, proteins and peptides and anti-neoplatics
Radio labeled and non-radio labeled test articles

Safety Research

General Toxicology
Conventional routes of administration:
- Oral
- Intravenous - bolus and infusion
- Intraperitoneal
- Intramuscular
- Subcutaneous
- Transdermal, dermal
Well Experienced in sub-chronic and chronic toxicology
Dermal Irritation
Target Animal Safety
Occular Toxicology

Surgical Research

Surgical Model Preparation
Cardiovascular
Coronary and Peripheral Stents
Medical Device
Orthopedics
Wound Healing
Experimental Surgery
Four Surgical Suites
Large Animal Necropsy
Flurosopy
Cardio-Ecography, EKG
Color-Doppler Ultrasonography
Body Composition
Bone Density
MRI and CT Imaging

Sinclair specializes in comprehensive large-animal support services, particularly for sub-chronic research projects at competitive prices. We excel at developing collaborative teams for complex large-animal projects.

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