Toxicology

Sinclair Research Center provides GLP-compliant general toxicology services in our new state-of-the-art facility near Columbia, Missouri.

Toxicology Services

  • Non-GLP (Discovery) and GLP Studies
    • Pilot/Range Finding Studies
    • Acute/Single Dose/MTD
    • 14-Day and 28-Day Repeat Dose
    • Sub-chronic and Chronic Exposures
  • Rodent and Non-Rodent
  • Repeat-Dose Dermal Irritation in Minipigs
  • Target Animal Safety Studies
  • FDA Redbook Feeding Trials

Test Facility

  • AAALAC Accredited Facility Since 1995
  • High Capacity for Small and Large Animals
  • Rodents
  • Canines
  • Miniature Swine (Sinclair, Yucatan, Hanford)
  • Non-Human Primates
  • Rabbits
  • Felines
  • Housing for Other Species Available (goat, sheep, horses)

Routes of Dose Administration

  • Parenteral (IV/SC/IM/IP)
  • IV Infusion
  • Ocular
  • Rectal/Intravaginal
  • Intranasal
  • Auricular
  • Oral (gavage/liquid/ tablet/capsule)
  • Dermal/Intradermal/Transdermal patch
  • Intracoronary/Intraventricular
  • Vascular Access Ports (VAP)(percutaneous access)

Supporting Components for Toxicology Studies

  • Toxicokinetics
  • GLP-Compliant Clinical Pathology
  • Board Certified Veterinary Ophthalmologist
  • Small and Large Animal Necropsy Suite
  • Board Certified Veterinary Cardiologist
  • Board Certified Veterinary Pathobiologist for Histopathology

Additional Resources:

Please contact us at:
573 387 4400
Online Request Form

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