News & Press Releases
Columbia, Mo., July 25, 2018 (Business Wire) — Sinclair Research, one of the nation’s leading providers of nonclinical services, has named Scott E. Boley, PhD, DABT, as vice president of toxicology. In this newly created role, he will have overall responsibility for driving the growth of Sinclair’s toxicology efforts and fostering relationships with new and current customers.
Columbia, Mo., June 13, 2018 (Business Wire) — Sinclair Research, one of the nation’s leading providers of preclinical services, is pleased to announce new scientific leadership with the arrival of Jeffrey Klein, Ph.D., DABT, as director of toxicology and dermatology. In this newly created role, Klein will be responsible for the company’s scientific direction in toxicology and dermatology services and their operational processes. He will drive the growth of Sinclair’s business model and foster positive relationships with new and current customers.
Klein joins Sinclair Research from EP Technologies LLC in Akron, Ohio, where he directed preclinical research including discovery, toxicology and management of active transdermal technology. He held a similar position at Noven Pharmaceuticals working with passive transdermal technology. With more than 15 years of industry experience, including serving as a study director at Ricerca Biosciences (now Concord Biosciences), Klein is an accomplished toxicology and drug development professional with extensive expertise in both technical study management and customer service. His preclinical knowledge and experience from the pharmaceutical and contract research organization industries will be of significant value to Sinclair and all its customers.
Columbia, Mo., May 16, 2018 (BUSINESS WIRE) — Sinclair Research, one of the nation’s leading providers of preclinical services, is pleased to announce new executive leadership with the arrival of Mark Lane, as director of business development. In this role, Lane will have responsibility for the San Francisco to Seattle corridor. He will be responsible for driving the growth of Sinclair’s IND enabling toxicology and efficacy models and fostering positive relationships with new and current customers.
North Callaway R-1 School District received a $70,000 grant this week from Sinclair Research of Callaway County.
"We want to help the local communities — that's our goal," -Dr. Guy Bouchard, President of Sinclair.
Sinclair Research Appoints Michael Eliel as Senior Director of Operations & Anthony Rohr as Consultant for Special Projects & Management Improvement
Columbia, Mo., Feb. 20, 2018 (Business Wire) — Sinclair Research, one of the nation’s leading providers of preclinical services, is pleased to announce new operational leadership with the arrival of Michael Eliel as senior director of operations. The company has also named Anthony Rohr as consultant for special projects and management improvement.
Columbia, Mo., Feb. 6, 2018 (Business Wire) — Sinclair Research, one of the nation’s leading providers of preclinical services, is pleased to announce new executive leadership with the arrival of G. Alex Wakefield, DVM, as vice president of research and operations.
Local and Systemic Effects of a Silver Nitrate Coated Indwelling Pleural Catheter in an Animal Model of Pleurodesis
Local and Systemic Effects of a Silver Nitrate Coated Indwelling Pleural Catheter in an Animal Model of Pleurodesis, has just been published on Taylor & Francis Online! Click the link above to get the full article!
Sinclair enjoyed a great year of compliance in 2017. In this year alone, Sinclair was inspected by five agencies and accrediting bodies, as well as numerous client audits, with successful outcomes across the board.
Check out “The Clinical Chemistry of Laboratory Animals, Third Edition”, which includes detailed chapters dedicated to descriptions of clinical chemistry-related topics specific to each laboratory species as well as organ/class-specific chapters. Sinclair was honored to have helped contribute to a Chapter we know a lot about, Chapter 5: The Laboratory Pig - Alain Stricker-Krongrad, Larry D. Brown, Guy Bouchard, M. Michael Swindle, and Stan W. Casteel.
We are excited to announce Alain Stricker-Krongrad and Derek Brocksmith won this year's Journal Award For Best Paper in Toxicologic Pathology for their paper Pigs in Toxicology: Breed Difference in Metabolism and Background Findings, congratulations to them and all involved! Click the link above to download the paper now!
Sinclair Research Center and Sinclair BioResources have recently contributed to a special issue of Toxicologic Pathology (Volume 44, Number 3, 2016) titled Swine in Translational Research and Drug Development. This issue focuses on the most recent developments of the use of swine, particularly miniature swine, in preclinical research; it also delves into the potential of future use of miniature swine in translational research and drug development. SRC and SBR contributed to the collection of background clinical and histopathological observations, vital to the interpretation of test article-related findings, in the article ”Miniature Swine Breeds in Toxicology and Drug Safety Assessments: What to Expect during Clinical and Pathology Evaluations”; they additionally contributed to the article “Background Pathological Changes in Minipigs: A Comparison of the Incidence and Nature among Different Breeds and Populations of Minipigs.”
Xybion Corporation announced today that Sinclair Research Center, LLC will deploy Xybion’s Total Preclinical Solution platform across Sinclair’s entire Laboratory operation. Sinclair and Xybion are collaborating to get ahead of the FDA SEND mandate while digitizing and automating Sinclair’s Lab to achieve significant productivity gains to support the growth of Sinclair’s business.
At the 2014 Annual ASR Meeting we won the Michael Deleo Award for our poster "Short-Acting & Long-Acting Buprenorphine Therapeutic Drug Levels Following Single Subcutaneous Administration in Diabetic Yucatan Miniswine"
Entitled ”Pharmacokinetic Compatibility Study of Lidocaine with EXPAREL in Yucatan Miniature Pigs” and published in ISRN Pharmaceutics in 2011, this study investigates the potential for EXPAREL to interact with lidocaine.
The 2013 edition of the Book of Normals is now available from our sister company, Sinclair BioResources, providing a comprehensive collection of normal values specifically for their miniature swine, including clinical pathology, body weights, growth charts, and organ weights.
Sinclair BioResources has been producing Yucatan, Sinclair and Hanford miniature swine for years. Their swine have been used extensively for toxicology, pharmacokinetic, metabolism, dermal and medical device studies; studies in these strains have been readily accepted by the FDA and other regulatory agencies. This new resource serves to provide support for clients as they sponsor and perform preclinical studies.