White Papers, Manuscripts, Posters & Book of Normals

Professional staff of Sinclair or collaborating clients have published these peer-reviewed manuscripts:

Peer-Reviewed Manuscripts

Tolerable Levels of Nonclinical Vehicles & Formulations Used in Studies by Multiple Routes in Multiple Species With Notes on Methods to Improve Utility

Comparative Cardiovascular Physiology & Pathology in Selected Lineages of Minipigs: Relation to Drug Safety Evaluation

The Importance of Minipigs in Dermal Safety Assessment: An Overview

Development of a Functional Observational Battery in the Minipig for Regulatory Neurotoxicity Assessments

Pharmacokinetics of Intravenous & Oral Metformin & R,S-Verapamil in Sinclair, Hanford, Yucatan & Göttingen Minipigs

The Importance of Minipigs in Dermal Safety Assessment: An Overview

Miniature Swine Breeds in Toxicology & Drug Safety Assesments

The Miniature Swine as a Model in Experimental & Translational Medicine

Miniature Swine Model of Phototoxicology Testing

Minipigs: Applications in Toxicology

Posters Presented at Scientific Meetings

Minipig Model of Atopic Dermatitis: Assessment of In Vivo & In Vitro Activity of Recombinant Porcine Interleukin-4 & Interleukin-13

Effect of Minoxidil on Hair Growth in Minipigs

Oral Cyclosporine A Immunosuppressive Therapy Leads to Systemic Toxicity in the Royal College of Surgeon Rats

Cardiac Ischemia & Reperfusion as a Model of Myocardial Infarction in New Zealand White Rabbits

Identification of Immunophenotyping Biomarkers & Characterization of Peripheral Blood Lymphocytes Populations Distribution in Minipigs

Electrophysiological Assessment of Cardiac Complications in Chronic Diabetic Minipigs

Laser Induced Choroidal Neovascularization (CNV) as a Model of Age-related Macular Degeneration (AMD) in the Minipig

Renal Complications in Chronic Diabetic Minipigs

Validation of a Functional Observational Battery in the Minipig for Regulatory Neurotoxicity Assessments

Comparative Sensitivity & Reliability of a Multi-Analytes Platform & a Multiplex Flow Cytometry in the Quantitation of Circulating Cytokines Level in a Mouse Model of Endotoxemia

Development of a Model of Dermal Inflammation & Irritation (Urticaria) in the Miniature Swine

Determinants of Ischemic Wound Healing in Diabetes: A Bipedicle Flap Wound Model in Diabetic Yucatan Miniature Swine

Preventing Process Drift While Improving Animal Welfare: Impact of Procedures Improvement in a Cat Colony

Characterization of Transdermal Pharmacokinetics of Ketoprofen in Sinclair & Gӧttingen Minipigs

Geometric Determinants of Full Thickness Wound Healing in Adult Male Yucatan Miniature Swine

Normal Organ Weight Data for the Yucatan Miniature Swine

Comparison of Human, Porcine and Rodent Wound Healing with New Miniature Swine Study Data

Why Use Miniature Swine in Dermal Research?

Testicular and Epididymal Histologic Changes Around the Period of Sexual Maturation in Yucatan Boars

Targeting to Overshadow Fears and Anxiety in Miniature Swine

Tape Stripping Repetitions Reduce the Stratum Corneum Inversely in Yucatan Miniature Swine

Normal Physiological and Pathological Values for the Sinclair Miniature Swine

Reproductive and Developmental Toxicology Assessment of Oral Dietary Calcium Formate in Yucatan Miniature Swine

Miniature Swine Model of Phototoxicity Testing

Blood Glucose (bG) Profiles Following IVGTT in Two Miniature Swine Lineages

Normal Physiological Values for Hanford Miniature Swine

Histopathological Background Findings in Hanford Miniature Swine

Yucatan Miniature Swine Surgical Glaucoma Model Development and Response to Therapy

Gastric Emptying OF Non-Disintegrating Radio-Opaque Tablets Administered Orally in the Yucatan Miniature Pig

Electroretinography (ERG) of C57BL/6 and NIH III Mice

Surgical and Non-Surgical Drug Delivery Methods in Miniswine Models

Differential Cardiovascular Physiology and Pathology in Selected Lineages of Miniature Swine

Characterization of a Long-Term Porcine Model for Diabetic Retinopathy

Dermal Toxicology Application Area Changes as Compared to Theoretical Total Surface Area of Hanford Miniature Swine Over 18 Weeks

Basal and Short-Term Food Denial Stress-Induced Plasma Cortisol in Four Lineages of Miniswine

Comparison of the Rabbit, Diabetic Miniature Swine and Non-Human Primate to Evaluate the Clinical Biopotency of Insulin

Characterization of Normal Skin Thickness for Various Body Regions, Ages and Genders of Yucatan Miniature Swine

Prevalence and Incidence of Cataracts in a Population of Diabetic Yucatan Miniswine

Short-Acting and Long-Acting Buprenorphine Therapeutic Drug Levels Following Single Subcutaneous Administration in Diabetic Yucatan Miniswine

Pharmacodynamic Glycemia Effects from Rapid and Long-Acting Insulins Administrated at Mealtime to Alloxan-Induced Diabetic Miniature Yucatan Swine

Book of Normals

Book of Normal 2013


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