| Background
• Domesticated miniature swine
• Sinclair acquired the Hanford colony from Charles
River
Laboratories (CRL).
Origin
• Hanford Labs started developing the Hanford in
1958 in
Richland, WA with two Palouse gilts and one
Pittman-
Moore boar. Later addition of more Pitman-Moore and
Swamp hog from Louisiana to further
reduce the size.
• Selection at 140 days old for fitness, skin and
hair color,
conformation, thickness of hair coat and
demeanor.
• Batelle Memorial Institute acquired the herd in
Mid-1960’s and introduced the Yucatan in the
foundation
stock.
• CRL assumed the breeding of the Hanford in 1982
at
Wilmington, MA.
• CRL moved the colony to Pittsfield, NH in 1983.
• Sinclair acquired the Hanford herd in 2002 and
moved
the colony to Columbia, MO.
• The colony is closed and fully pedigreed.
Characteristics
• Purpose-bred, socialized and vaccinated.
• Looks like traditional farm pigs.
• White skin and haircoat making them excellent
for dermal studies.
• Lack of fat making the Hanford a good model
for surgical studies.
• Heart size very similar to human with few collaterals
making the Harford an excellent cardiovascular
model.
• Free from common domestic swine diseases; e.g.
leptospirosis, brucellosis, pseudorabies,
transmissible
gastroenteritis, porcine reproductive respiratory syndrome,
toxoplasmosis, etc.
• Well adapted to the laboratory environment and
very
useful when only limited space is available.
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