Summary of Sinclair Research Center Products and Services
Sinclair is an AAALAC accredited preclinical research facility located on 200 acres near Columbia, Missouri. The three main offerings of Sinclair are production and sale of miniature swine, production and sale of bio-products, and in-vivo preclinical research services.

Sinclair’s New Research Facility Operational
Sinclair is proud to announce that our new state-of-the-art preclinical research facility is complete and in full operation near Columbia, Missouri. The facility has approximately 130,000 square feet designed with current technological expertise and with the welfare of each species in mind. Sinclair has significant large animal experience, and a high capacity to house large animals for acute, sub-chronic, and chronic study designs. Species capabilities include rodents, rabbits, poultry, cats, dogs, swine, horses, goats, and sheep. Sinclair maintains large colonies of cats, dogs, and miniature swine.

Preclinical (Nonclinical) Research Service Offerings
Sinclair offers a variety of preclinical (nonclinical) research services to the human pharmaceutical and medical device, animal health, and consumer product industries. Programs include efficacy/pharmacodynamics, DMPK, toxicology, and surgical services. All standard routes of administration are offered using both non-radiolabelled and radiolabelled test articles. We can support drug and device research from discovery through initial regulatory submission.

Research Staff
Sinclair has a friendly, experienced, and motivated veterinary and research staff who provide you with quality study execution, excellent communication, and timely reporting. Experienced study directors and principal investigators, assisted by support staff, manage studies vertically, maintaining full control over your study. Complementing the research personnel are competent veterinary staff members who participate in the study conducting procedures, collecting samples, and maintaining animal health. Qualified laboratory animal personnel provide husbandry and care for the animals. A full training program is in place at Sinclair and all personnel have current training records.

Regulatory Compliance and Quality Assurance
Sinclair complies with a number of agencies. We are USDA licensed as a breeder (43-A-2499) and research facility (43-R-0109). We are AAALAC accredited and have maintained this accreditation since 1995. The animal care and veterinary program is in compliance with the Guide for the Care and Use of Laboratory Animals. Sinclair also has an Assurance Statement filed with PHS.

Sinclair is fully GLP compliant and our personnel have many years of GLP experience. Sinclair has an independent Quality Assurance Unit (QAU) that audits the facility, protocols, in-life critical phases, raw data, and reports for GLP studies. Sinclair is inspected by the FDA on an ongoing basis. Inspections in the spring of 2002, spring of 2004, and late fall of 2005 were all classified as NAI (no objectionable conditions or practices were found during the inspection), and no 483s were issued.

Alliance Partner Services
Sinclair collaborates with several centers of expertise which provide complementary services to the research program, such as bioanalytical, clinical pathology, and histopathology. Furthermore, Sinclair’s clients have access to a large number of well known expert consultants due to Sinclair’s advantageous location near the University of Missouri-Columbia’s College of Veterinary Medicine, Health Center and Teaching Hospital, and the Ellis Fischel Cancer Hospital.

Visit Sinclair Research Center, Inc.
We would welcome your visit to Sinclair Research Center. We truly have an impressive facility, and we invite you to come see our program and meet our research staff. Call and schedule a visit today!